Circulating Tumor DNA Testing in Curatively Resected Colorectal Cancer and Salvage Resection

In this cohort study of patients with stage II to IV colorectal cancer who underwent curative-intent resection, the addition of serial tumor-informed ctDNA assay to the standard NCCN-recommended surveillance had limited clinical benefits. Additional prospective research is needed to clarify the value of ctDNA testing in the surveillance setting.

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Publication Details

Journal
JAMA Network Open
Published
2024-12-27
DOI
https://doi.org/10.1001/jamanetworkopen.2024.52661
Citations
5
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
1.43
Controls
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article

Circulating Tumor DNA Testing in Curatively Resected Colorectal Cancer and Salvage Resection

Jingran Ji, Yuman Fong, Lily Lai, Laleh Golkar Melstrom et al.
5 citations
JAMA Network Open
Cancer Genomics and Diagnostics
1.43
article

Circulating Tumor DNA Testing in Curatively Resected Colorectal Cancer and Salvage Resection

Jingran Ji, Yuman Fong, Lily Lai, Laleh Golkar Melstrom, Kurt Melstrom, Marwan Fakih, Chongkai Wang, Mustafa Raoof, Ajay Goel, Andreas M. Kaiser, Yasmin Zerhouni
article en
5 citations

Abstract

In this cohort study of patients with stage II to IV colorectal cancer who underwent curative-intent resection, the addition of serial tumor-informed ctDNA assay to the standard NCCN-recommended surveillance had limited clinical benefits. Additional prospective research is needed to clarify the value of ctDNA testing in the surveillance setting.

JAMA Network OpenVol. 7(12)
City of Hope (US)
Good health and well-being
Openalex Percentile: Top 17%
Cancer Genomics and Diagnostics
1.43
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