Double Whammy: A Case Report of Immune Checkpoint Inhibitor Colitis and Concomitant Cytomegalovirus Colitis in a Patient on Nivolumab
Immune checkpoint inhibitors commonly cause gastrointestinal immune-related adverse effects. These patients also carry an increased risk of concomitant infections. This 66-year-old man with immune checkpoint inhibitor colitis was discovered to have concurrent <i>Yersinia</i> and <i>Cytomegalovirus</i> colitis. Such infections may mimic or complicate disease course. Hence, clinicians must monitor patient symptoms, have a low threshold for infectious testing and colonoscopy, and consider treatment strategies to mitigate their risk.
Authors
- Vinay Jahagirdar (ORCID: https://orcid.org/0000-0001-6685-1033)
- Kimberly Sanders
- Wendell Clarkston
- Sreenivasa S. Jonnalagadda (ORCID: https://orcid.org/0000-0003-4777-0849)
- Rajiv Chhabra (ORCID: https://orcid.org/0000-0002-0417-2032)
- John P. Campbell (ORCID: https://orcid.org/0000-0001-9989-6158)
- Misha Gautam (ORCID: https://orcid.org/0000-0002-3826-2132)
- Himil Mahadevia (ORCID: https://orcid.org/0000-0002-2083-5510)
- Pamela B. Sylvestre
Institutions
- Emory University (US)
- Saint Luke's Hospital (US)
- University of Missouri–Kansas City (US)
Publication Details
- Journal
- ACG Case Reports Journal
- Published
- 2024-12-27
- DOI
- https://doi.org/10.14309/crj.0000000000001569
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- American College of Gastroenterology