A young adult patient with Philadelphia positive acute lymphoblastic leukemia presenting with extreme hyperleukocytosis
Extreme hyperleukocytosis (Leukocyte count >200 × 10<sup>9</sup>/L) in an adolescent young adult (AYA) patient with B-ALL could result in mild symptoms of leukostasis. Hyperleukocytosis requires prompt initiation of therapy with adequate hydration, cytoreduction and prevention of tumor lysis. Ph + B-ALL may present with extreme hyperleukocytosis and may be resistant to initial pre-phase therapy. In such cases, leukocytapheresis is beneficial in reducing the leukocyte count as well as controlling the symptoms.
Authors
- Şule Mine Bakanay (ORCID: https://orcid.org/0000-0003-3941-0368)
- İmdat Dılek
- Gulten Tikit (ORCID: https://orcid.org/0009-0002-4859-8083)
- Elif Yucesu
- Aliye Serpil Sarıfakıoglu
Institutions
- Memorial Ankara Hospital (TR)
- Ankara Yıldırım Beyazıt University (TR)
Publication Details
- Journal
- Clinical Case Reports
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1002/ccr3.9512
- Citations
- 1
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.45