Retinal Docosahexaenoic Acid Is Significantly Reduced in Diabetic Humans and Mice: Possible Relationship to Diabetic Retinopathy
Retinal DHA is reduced in diabetic humans and mice, which is associated with a thinning of retina and functional defects in diabetic mice. Enriching retinal DHA through diet may be beneficial in the prevention and treatment of diabetic retinopathy.
Authors
- Zeenat Farooq
- Basma Baccouche
- J. Jason McAnany (ORCID: https://orcid.org/0000-0003-1192-3487)
- Xincheng Yao (ORCID: https://orcid.org/0000-0002-0356-3242)
- Brian Thomas Layden (ORCID: https://orcid.org/0000-0003-2176-5654)
- Jason C. Park (ORCID: https://orcid.org/0000-0002-8738-5999)
- Papasani V. Subbaiah (ORCID: https://orcid.org/0000-0002-9376-8582)
- Guangying Ma (ORCID: https://orcid.org/0000-0002-7990-1420)
- Sugasini Dhavamani (ORCID: https://orcid.org/0000-0001-9077-9940)
- Poorna C. R. Yalagala (ORCID: https://orcid.org/0000-0001-8472-8477)
- Andrius Kazlauskas (ORCID: https://orcid.org/0000-0003-1919-3327)
- Onkar B. Sawant
Institutions
- University of Illinois Chicago (US)
- Jesse Brown VA Medical Center (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-12-27
- DOI
- https://doi.org/10.1167/iovs.65.14.39
- Citations
- 5
- Primary Topic
- Eicosanoids and Hypertension Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Research to Prevent Blindness
- Retina Research Foundation
- National Institutes of Health