Optimized Spheroid Model of Pancreatic Cancer Demonstrates Influence of Macrophage–T Cell Interaction for Intratumoral T Cell Motility
Motility analysis using a spheroid model of pancreatic cancer is a more sophisticated alternative to in vitro cytotoxicity assays measuring spheroid size. Ultimately, an optimized spheroid model might replace at least some aspects of animal experiments investigating T cell effector function.
Authors
- Magdalena Huber (ORCID: https://orcid.org/0000-0002-2963-0693)
- Katrin Roth (ORCID: https://orcid.org/0000-0002-3144-1162)
- Christian Bauer (ORCID: https://orcid.org/0000-0003-1349-0160)
- Vincent Zimmer (ORCID: https://orcid.org/0000-0002-6298-4717)
- Veronika Lutz (ORCID: https://orcid.org/0000-0002-3139-0916)
- Malte Buchholz (ORCID: https://orcid.org/0000-0002-2833-995X)
- Elena Nasiri
- Thomas M. Gress (ORCID: https://orcid.org/0000-0002-9333-5461)
- Benedikt Slusny
Institutions
- Philipps University of Marburg (DE)
- Deggendorf Institute of Technology (DE)
Publication Details
- Journal
- Cancers
- Published
- 2024-12-27
- DOI
- https://doi.org/10.3390/cancers17010051
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.24
Funders
- Deutsche Forschungsgemeinschaft