Utilization of plant-based foods for effective prevention of chronic diseases: a longitudinal cohort study

The present study examined optimal dietary patterns of eight plant-based foods for preventing chronic diseases, including hypertension, stroke, myocardial infarction, and diabetes, using data from the China Health and Nutrition Survey (CHNS). We applied generalized estimating equations to assess time-based changes and gender differences, using residual balancing weights to control time-varying confounders, and employed a restricted cubic spline model to explore dose-response relationships by gender. The findings suggested that a high intake of vegetables and whole grains, along with moderate amounts of fruits, fungi and algae, could help reduce the risk of developing these four chronic diseases simultaneously. Additionally, men could benefit from moderate refined grain consumption, while women should consider increasing their intake of nuts and seeds. Our results indicated that adopting a plant-based diet could provide non-linear protective effects against chronic diseases, with the magnitude of this protection varying by gender.