Drugs with secondary hypoglycemic effect

The problem of hypoglycemia induced by non-diabetic drugs, which is increasingly reported, has been studied. The hypoglycemic side effect of drugs is explained by different mechanisms and manifests individually depending on age, gender, comorbidities. A special role belongs to the associated administration of drugs and the interaction between them. Data from the specialized literature (case reports and medical databases) were selected and analyzed, with the aim of identifying drugs with hypoglycemic potential, mechanisms of action, associated risk factors, including strategies of prevention and management of drug-induced hypoglycemia. The study reports a variety of non-diabetic drugs, the administration of which is associated with the risk of developing hypoglycemia, including beta-blockers, fluoroquinolones, converting enzyme inhibitors (ACE), and others. The mechanisms by which they may affect glucose levels have been detailed, as well as the importance of careful patient monitoring and treatment adjustment. Druginduced hypoglycemia is a significant clinical problem that requires a multidisciplinary approach to its prevention and management. Patient education and effective doctor-patient communication are essential to minimize risks and improve treatment safety.