#Opioids: A Mixed-Methods Examination of Top Opioid-Related Content on TikTok

This study revealed polarizing opinions within opioid-related content on TikTok. The two main stances, dangers of nonmedical opioid use and advocacy for the availability of prescription opioids for pain management, represent nationwide tensions between the opioid and chronic pain crises. The vast audience TikTok garners presents an opportunity for disseminating opioid education, harm-reduction strategies, and treatment options for opioid use disorder that were largely absent among the posts analyzed.