Heat shock protein 70 levels in children with nephrotic syndrome

Our study demonstrates that uHSP70 levels are elevated in SSNS prior to treatment and decrease with prednisolone therapy, reflecting reduced renal stress and damage. uHSP70 may be a useful biomarker for monitoring renal damage and treatment response. Serum and urine levels of HSP70, as well as uHSP70/Cre ratios, did not differentiate between frequent and infrequent relapses.

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Publication Details

Journal
The Turkish Journal of Pediatrics
Published
2024-12-27
DOI
https://doi.org/10.24953/turkjpediatr.2024.4575
Citations
1
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.34
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article

Heat shock protein 70 levels in children with nephrotic syndrome

Alev Yılmaz, Bağdagül Aksu, Asuman Gedikbaşı, Zeynep Yürük Yıldırım
1 citations
The Turkish Journal of Pediatrics
Renal Diseases and Glomerulopathies
0.34
article

Heat shock protein 70 levels in children with nephrotic syndrome

Alev Yılmaz, Bağdagül Aksu, Asuman Gedikbaşı, Zeynep Yürük Yıldırım
article en
1 citations

Abstract

Our study demonstrates that uHSP70 levels are elevated in SSNS prior to treatment and decrease with prednisolone therapy, reflecting reduced renal stress and damage. uHSP70 may be a useful biomarker for monitoring renal damage and treatment response. Serum and urine levels of HSP70, as well as uHSP70/Cre ratios, did not differentiate between frequent and infrequent relapses.

The Turkish Journal of PediatricsVol. 66(6)
Istanbul University (TR)
Good health and well-being
Openalex Percentile: Top 32%
Renal Diseases and Glomerulopathies
0.34
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