Factors and outcomes associated with under‐ and overdiagnosis of sepsis in the first hour of emergency department care

This prospective single-academic center study identified patient subgroups at risk of impaired diagnostic accuracy of sepsis, with clinicians often overdiagnosing rather than underdiagnosing these groups. Prompt abnormal laboratory test results can "rescue" initial missed diagnoses, serving as potential clinician- and systems-level intervention points to reduce missed diagnoses. Missed diagnoses delayed antibiotics, but not mortality after controlling for severity of illness.

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Publication Details

Journal
Academic Emergency Medicine
Published
2024-12-27
DOI
https://doi.org/10.1111/acem.15074
Citations
5
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.93
Controls
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article

Factors and outcomes associated with under‐ and overdiagnosis of sepsis in the first hour of emergency department care

Sarah K. Knack, Matthew E. Prekker, Olivia Kaus, Brian E. Driver et al.
5 citations
Academic Emergency Medicine
Sepsis Diagnosis and Treatment
1.93
article

Factors and outcomes associated with under‐ and overdiagnosis of sepsis in the first hour of emergency department care

Sarah K. Knack, Matthew E. Prekker, Olivia Kaus, Brian E. Driver, Ellen Maruggi, Walker Tordsen, Nathaniel L. Scott, Michael A. Puskarich, Sureshwar Pandey, Sarah J. Ringstrom
article en
5 citations

Abstract

This prospective single-academic center study identified patient subgroups at risk of impaired diagnostic accuracy of sepsis, with clinicians often overdiagnosing rather than underdiagnosing these groups. Prompt abnormal laboratory test results can "rescue" initial missed diagnoses, serving as potential clinician- and systems-level intervention points to reduce missed diagnoses. Missed diagnoses delayed antibiotics, but not mortality after controlling for severity of illness.

Academic Emergency MedicineVol. 32(3)
University of Minnesota (US), Hennepin Healthcare Research Institute (US)
Good health and well-being
Openalex Percentile: Top 12%
Sepsis Diagnosis and Treatment
1.93
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