Diagnostic performance of metagenomic next-generation sequencing among hematological malignancy patients with bloodstream infections after antimicrobial therapy
The antimicrobial treatment will greatly reduce the positive rate of mNGS. The duration of mNGS is significantly longer than that of BC. The prolonged duration of mNGS suggests an increased risk of septic shock and could be identified as a high-risk factor of adverse infection outcome, requiring more aggressive anti-infective treatment measures.
Authors
- Yueyi Xu
- Miaoxin Peng
- Yonggong Yang (ORCID: https://orcid.org/0000-0002-6475-2696)
- Ting Xie (ORCID: https://orcid.org/0000-0003-4769-986X)
- Bing Chen (ORCID: https://orcid.org/0000-0003-0168-8532)
- Tong Zhou (ORCID: https://orcid.org/0000-0002-9618-7011)
- Peipei Xu (ORCID: https://orcid.org/0000-0002-7035-6745)
- Xuefang Cao (ORCID: https://orcid.org/0000-0002-1633-4895)
- Jian Ouyang (ORCID: https://orcid.org/0009-0009-6821-0243)
Institutions
- Nanjing Drum Tower Hospital (CN)
- Zhejiang Medicine (China) (CN)
Publication Details
- Journal
- Journal of Infection
- Published
- 2024-12-27
- DOI
- https://doi.org/10.1016/j.jinf.2024.106395
- Citations
- 10
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 2.83
Funders
- Government of Jiangsu Province
- Nanjing University
- Servier