Different orthology inference algorithms generate similar predicted orthogroups among Brassicaceae species

Three algorithms-OrthoFinder, SonicParanoid, and Broccoli-are helpful for initial orthology predictions. Results produced using OrthNet were generally outliers but could still provide detailed information about gene colinearity. With our Brassicaceae dataset, slight discrepancies were found across the orthology inference algorithms, necessitating additional analyses such as tree inference to fine-tune results.

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Publication Details

Journal
Applications in Plant Sciences
Published
2024-12-25
DOI
https://doi.org/10.1002/aps3.11627
Citations
1
Primary Topic
Genomics and Phylogenetic Studies
Type
article
Field-Weighted Citation Impact
0.23

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article

Different orthology inference algorithms generate similar predicted orthogroups among Brassicaceae species

Irene T. Liao, Karen E. Sears, Lachezar A. Nikolov, Lena C. Hileman
1 citations
Applications in Plant Sciences
Genomics and Phylogenetic Studies
0.23
article

Different orthology inference algorithms generate similar predicted orthogroups among Brassicaceae species

Irene T. Liao, Karen E. Sears, Lachezar A. Nikolov, Lena C. Hileman
article en
1 citations

Abstract

Three algorithms-OrthoFinder, SonicParanoid, and Broccoli-are helpful for initial orthology predictions. Results produced using OrthNet were generally outliers but could still provide detailed information about gene colinearity. With our Brassicaceae dataset, slight discrepancies were found across the orthology inference algorithms, necessitating additional analyses such as tree inference to fine-tune results.

Applications in Plant SciencesVol. 13(1)
University of Kansas (US), University of California, Los Angeles (US), Indiana University Bloomington (US)
National Science Foundation
Life in Land
Openalex Percentile: Top 40%
Genomics and Phylogenetic Studies
0.23
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