FIBRILLARY GLOMERULONEPHRITIS: THE IMPORTANCE OF DIAGNOSTIC APPROACH

Fibrillary Glomerulonephritis(FGN) is rare glomerular disease characterized by microscopic hematuria, proteinuria, hypertension and renal insufficiency.Crescentic pattern of FGN is uncommon and would be diagnosed as rapidly progressive renal failure unless Electron Microscopy and/ or special stains are done. We present a case report of a young male who presented as nephrotic syndrome who was diagnosed to have crescentic GN and was revised to crescentic FGN after electron microscopy and immunohistochemical staining with DNAJB9 stain. Patient treatment was changed to Rituximab. The case emphasizes the use of Electron microscopy and special stains in diagnosing rare diseases and importance of diagnostic approach to Fibrillary Glomerulonephritis.