Current status and future development direction of treatment for essential tremor

Essential tremor (ET) is a common movement disorder that continues to increase in prevalence. Currently used drugs such as propranolol and primidone have limited efficacy and are associated with a high number of side effects. For individuals with serious conditions, deep brain stimulation (DBS) is an effective therapy, but its high cost and potential surgical complications limit widespread use. Emerging therapies including Magnetic resonance-guided focused ultrasound (MRgFUS) and Gamma Knife radiosurgery thalamotomy (GKT) offer new options for treatment, but their long-term effects still need to be proven. Future treatment directions should focus on personalized and low side-effect regimens to enhance patients' quality of life. This article reviews existing treatments and discusses future directions.