Research Progress about Exploring the Impact of Jet Lag on Circadian Rhythms

Circadian rhythm, one of the fundamental laws of nature, plays an essential role in maintaining life processes. However, it is challenged by a modern situation known as jet lag. Jet lag brings disruption to circadian rhythm, breaking people's normal routine and causing troubles to peoples lives. For the past few years, jet lag have been reported frequently. More researchers have realized the importance and complexity of jet lag. Jet lag can arise from travel crossing time zones as well as from shift works, impacting several aspects of life activity including metabolism, mental health, intestinal health et cetera. Beyond the macroscopical symptoms, microcosmic alterations are as important as the symptoms. Gene expression patterns can be varied by chronic jet lag even rewrote by the chronic jet lag and have long-term effects. Fortunately, several researches have revealed the possibility to lessen the influence of jet lag to fitness. Compared to the last century, people live in modern society have more optional methods to enjoy a much more comfortable life. Melatonin therapy and chronotherapy have been presented by scientists to settle the jet lag, But for the treatment of jet lag, there are still lots of details need to be considered.