A potential therapeutic role of resveratrol in mitigating hepatotoxicity induced by paracetamol and alcohol
Resveratrol and silymarin effectively counteract ethanol- and APAP-induced hepatotoxicity by mitigating oxidative stress and inflammation. Their combined use demonstrates a synergistic benefit, as evidenced by enhanced biochemical and histological improvements. These findings support the potential therapeutic role of these natural agents in managing drug-induced liver injury.
Authors
- Manjunatha Goud (ORCID: https://orcid.org/0000-0002-7195-6945)
- Vijaya Paul Samuel
- Naveen Kumar (ORCID: https://orcid.org/0000-0003-2805-779X)
- Noha Hashmi
- Mahra Ali Almazrouei
- Ruaa Faris Tawfeeq
- Yusur Abbas Mahmood
- Maitha Rashed Abdulla
- Bashayer Alshamsi
Institutions
- Ras al-Khaimah Medical and Health Sciences University (AE)
Publication Details
- Journal
- Journal of Complementary and Integrative Medicine
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1515/jcim-2024-0380
- Citations
- 1
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.47