Changes in the Level of Vitamin D3 and Calcium in Patients with Chronic Kidney Disease

Abstract Background: Chronic kidney disease (CKD) is a global public health issue that is linked to a variety of anomalies in biology and hematology, resulting in increased mortalities and morbidity. Objectives: Aim of this study was to estimate the vitamin D3 and calcium with other parameters in people with CKD. Materials and Methods: Fifty male patients and 40 healthy men were included, and the age of the participants in this study ranged from 40 to 50 years old. Samples were collected during the period from November 2022 to December 2022. Results: The result showed a significant decrease in vitamin D3 and calcium in patients group 16.99 ± 3.84 ng/mL and 6.23 ± 0.39 mg/dL, respectively, compared with healthy group 35.50 ± 5.93 ng/mL and 9.46 ± 0.58 mg/dL, respectively, a significant rise in the urea, creatinine and uric acid levels in patients 223.90 ± 46.40 mg/dL, 12.01 ± 2.01 mg/dL, and 9.34 ± 0.90 mg/dL, respectively, compared with healthy group 25 ± 5.75 mg/dL, 0.67 ± 0.22 mg/dL, and 4.72 ± 0.85 mg/dL, respectively. Conclusions: Results showed reduced concentrations of vitamin D3 and calcium, and elevated in concentrations of urea, creatinine, and uric acid in patients.