Blood and urinary cytokine balance and renal outcomes at orthopaedic surgery
Reductions in ratios of urine anti-inflammatory and proinflammatory biomarkers in PTOS-AKI patients suggest that the renal anti-inflammatory response is protective against the proinflammatory response in patients who do not develop PTOS-AKI. Detection of proinflammatory and anti-inflammatory biomarkers both pre- and post-operatively may be useful in detecting patients at risk of developing AKI after orthopaedic surgery.
Authors
- Peter J. Fitzgerald
- Allister Irvine
- John Lamont
- Mark W. Ruddock (ORCID: https://orcid.org/0000-0003-0988-2436)
- Anna Domanska
- Joanne Watt
- Gavin McLean
- William T. McBride
- Mary Jo Kurth (ORCID: https://orcid.org/0000-0002-8040-8270)
Institutions
- Belfast Health and Social Care Trust (GB)
- Randox (United Kingdom) (GB)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-12-26
- DOI
- https://doi.org/10.3389/fendo.2024.1441632
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Queen's University Belfast
- Queen's University