Systematic Assessment of Eras: Effectiveness and Application in Surgical Interventions for Colorectal Cancer

Introduction: Over the past 20 years, Enhanced Recovery After Surgery (ERAS) has gained popularity in colorectal cancer surgery. In addition, single-port laparoscopic surgery has been shown to have advantages. In colon cancer surgery, single-port laparoscopic surgery and ERAS can improve short-term results. However, whereas the former depends on surgical ability, the latter requires multidisciplinary teamwork. The goal of this project is to investigate the application and outcomes of ERAS protocols throughout the whole continuum of care for colorectal cancer surgery. Examine the details of how ERAS protocols enhance surgical results, with an emphasis on comprehending the subtleties of its use in the treatment of colorectal cancer and the possible obstacles to its broad adoption. Materials and Methods: A literature review was conducted, spanning Medline, Embase, and Cochrane Library databases for research conducted between January 2007 and June 2022 and involved specific keywords. The analysis included studies that had to meet two essential criteria: least investigation period of 30 days and compliance with a minimum of four out of the five core components of ERAS. Results: Following a comprehensive assessment, five studies satisfied the inclusion criteria. Among these studies, there were two ‘Randomized Controlled Trials’ (RCTs) and three Observational studies. These studies collectively encompassed 1454 patients: 820 patients treated following ERAS protocols, and 634 patients treated with non-ERAS protocols. Conclusion: The evidence supporting ERAS’s potential to enhance patient outcomes and its implementation challenges is compiled in this article. That allows to guide future research, enhance treatment following colorectal cancer surgery, and influence clinical practice.