Metallothionein-1A (MT1A) Gene Variability May Play a Role in Female Frailty: A Preliminary Study
Although its associations do not survive Bonferroni correction, this exploratory study suggests a sex-specific influence of <i>MT1A</i> variability in frailty, likely affecting zinc availability, aligning with ongoing research on sex differences in frailty risk and progression. Larger studies are needed to validate these findings and clarify the mechanisms behind MTs' variability in frailty progression.
Authors
- Francesco De Rango (ORCID: https://orcid.org/0000-0002-2328-8487)
- Giuseppe Passarino (ORCID: https://orcid.org/0000-0003-4701-9748)
- Giuseppina Rose (ORCID: https://orcid.org/0000-0002-4264-4184)
- Serena Dato (ORCID: https://orcid.org/0000-0003-2589-7929)
- Paolina Crocco (ORCID: https://orcid.org/0000-0001-7803-5340)
- Rossella La Grotta
Institutions
- University of Calabria (IT)
Publication Details
- Journal
- Genes
- Published
- 2024-12-26
- DOI
- https://doi.org/10.3390/genes16010015
- Citations
- 1
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 0.31