Metabolic Syndrome in Childhood Cancer Survivors

Background: Cancer is the second leading cause of death in Iraq and the remarkable improvements in pediatric cancer treatment protocols in the last few decades resulted in increase the number of childhood cancer survivors. Unfortunately, these improvements were associated with the incidence of metabolic syndrome in Childhood cancer survivors. Method: A case control study was carried out in Basra children specialty hospital/oncology center to detect the frequency of metabolic syndrome in Childhood cancer survivors. A total of 50 (26 male and 24 female) cancer survivor subjects and 50 (26 male and 24 female) as control were included in the study. The mean of age of test group was 10.8 ± 6.4 year and the control group was 10.6 ± 6.3 year. A special designed questionnaire was used for the purpose of the study. Measurements in terms of height, weight, body mass index, blood pressure were recorded. The biochemical investigations included in the study were fasting blood sugar, serum insulin like growth factor 1, serum cholesterol, triglycerides, low density lipoprotein and high-density lipoprotein. Both hematological and solid tumors with their treatment modality and off therapy time were included.