High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 update
Carbapenem-resistant <i>Pseudomonas aeruginosa</i> is defined by the World Health Organization as a "high priority" in developing new antimicrobials. Indeed, the emergence and spread of multidrug-resistant (MDR) or extensively drug-resistant (XDR) bacteria increase the morbidity and mortality risk of infected patients. Genomic variants of <i>P. aeruginosa</i> that display phenotypes of MDR/XDR have been defined as high-risk global clones. In this mini-review, we describe some international high-risk clones that carry β-lactamase genes that can produce chronic colonization and increase infected patients' morbidity and mortality rates.
Authors
- Santiago Partida‐Sánchez (ORCID: https://orcid.org/0000-0003-2996-9440)
- Miguel A. Ares (ORCID: https://orcid.org/0000-0003-2574-958X)
- Verónica Roxana Flores-Vega (ORCID: https://orcid.org/0000-0001-8830-4284)
- Roberto Rosales-Reyes (ORCID: https://orcid.org/0000-0001-9519-8766)
- Vianney Ortiz‐Navarrete (ORCID: https://orcid.org/0000-0001-6546-9713)
Institutions
- Nationwide Children's Hospital (US)
- Mexican Social Security Institute (MX)
- Centro Medico Nacional Siglo XXI (MX)
- The Ohio State University (US)
- Instituto Politécnico Nacional (MX)
- Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (MX)
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Heliyon
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e41540
- Citations
- 14
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 2.38
Funders
- Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional