Effect of medium-chain triglycerides and whey protein isolate preloads on glycaemia in type 2 diabetes: a randomized crossover study
Sequential consumption of MCT and WPI preloads did not affect diurnal or 24-h glycaemia but lowered PPG and 24-h glycaemic variability in individuals with T2D. These effects were associated with increased circulating β-hydroxybutyrate, PYY, and GIP, and suppression of appetite. This trial was registered at clinicaltrials.gov as NCT04905589 (https://clinicaltrials.gov/study/NCT04905589).
Authors
- Kostas Tsintzas (ORCID: https://orcid.org/0000-0002-3405-5769)
- Odd Erik Johansen (ORCID: https://orcid.org/0000-0003-2470-0530)
- M Keeton
- Bernard Cuenoud (ORCID: https://orcid.org/0000-0001-5120-1740)
- Leonidas G. Karagounis (ORCID: https://orcid.org/0000-0003-2403-3387)
- Pardeep Pabla
- Matthew F. Jacques
- Joanne Mallinson (ORCID: https://orcid.org/0000-0003-1275-2448)
- Sara Brown (ORCID: https://orcid.org/0000-0002-8511-0449)
- Scott Cooper (ORCID: https://orcid.org/0000-0002-5118-5733)
- Aline Nixon
- Melanie Marshall
Institutions
- University of Nottingham (GB)
- Nestlé (Switzerland) (CH)
- Arthritis UK (GB)
- Institute of Social and Preventive Medicine (CH)
- Queen's Medical Centre (GB)
- Australian Catholic University (AU)
Publication Details
- Journal
- American Journal of Clinical Nutrition
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1016/j.ajcnut.2024.12.022
- Citations
- 4
- Primary Topic
- Diabetes Management and Research
- Type
- article
- Field-Weighted Citation Impact
- 1.43