Assessment of Visual Evoked Potential in the Non-diabetic Offspring of Type II Diabetic Individuals - A Cross Sectional Study

Abstract Introduction: Visual evoked potential (VEP) is a non-invasive tool to detect retinopathy at early stages, and it can be used as a predictive marker for diabetic retinopathy. The study aimed to analyse VEP in non-diabetic offspring of type 2 diabetic and non-diabetic parents. Methodology: A cross-sectional observational study was conducted among 53 non-diabetic and normotensive offspring of type 2 diabetic and non-diabetic parents aged 18-25 years. Visual acuity and field of vision were assessed, and height, weight, and BMI were recorded. VEP was recorded using the standard operating procedure in the electrophysiology lab. Results: There is no significant difference in age, height, weight, and BMI between the two groups. Significant difference in P100 latency was observed in the right eye ( P value is 0.003) and left eye ( P value is 0.001) between offspring of diabetic parents and non-diabetic parents. Whereas no significant difference is observed in N75 latency, N 145 latency, and N75-P100 amplitude. Conclusions: The current study suggests that there is alteration in the VEP parameters in non-diabetic offspring of type 2 diabetic parents compared to offspring of non-diabetic parents.