A case of kerion celsi caused by Trichophyton tonsurans with dermatophytid reaction mimicking a drug eruption and endothrix infection confirmed in pathological tissue

We report a case of kerion celsi caused by <i>Trichophyton tonsurans</i> in a teenage male judo athlete, presenting with a lesion in the occipital region. Following the initiation of systemic antifungal therapy, the patient developed a dermatophytid reaction, necessitating differentiation from a drug eruption. Direct microscopy of the affected area confirmed the presence of fungal elements, and histopathological examination revealed endothrix invasion, supporting the continuation of treatment. A drug-induced lymphocyte stimulation test for terbinafine, conducted post-treatment, was negative. This case highlights the importance of distinguishing dermatophytid reactions from drug eruptions to ensure uninterrupted antifungal therapy.

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Publication Details

Journal
Medical Mycology Case Reports
Published
2024-12-25
DOI
https://doi.org/10.1016/j.mmcr.2024.100691
Primary Topic
Nail Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

A case of kerion celsi caused by Trichophyton tonsurans with dermatophytid reaction mimicking a drug eruption and endothrix infection confirmed in pathological tissue

Makoto Ishiai, Hiroshi Tanabe
Medical Mycology Case Reports
Nail Diseases and Treatments
article

A case of kerion celsi caused by Trichophyton tonsurans with dermatophytid reaction mimicking a drug eruption and endothrix infection confirmed in pathological tissue

Makoto Ishiai, Hiroshi Tanabe
article en

Abstract

We report a case of kerion celsi caused by <i>Trichophyton tonsurans</i> in a teenage male judo athlete, presenting with a lesion in the occipital region. Following the initiation of systemic antifungal therapy, the patient developed a dermatophytid reaction, necessitating differentiation from a drug eruption. Direct microscopy of the affected area confirmed the presence of fungal elements, and histopathological examination revealed endothrix invasion, supporting the continuation of treatment. A drug-induced lymphocyte stimulation test for terbinafine, conducted post-treatment, was negative. This case highlights the importance of distinguishing dermatophytid reactions from drug eruptions to ensure uninterrupted antifungal therapy.

Medical Mycology Case ReportsVol. 47
Tenri Hospital (JP)
Kanazawa Medical University
Good health and well-being
Openalex Percentile: Top 64%
Nail Diseases and Treatments
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