Assessment of the influence of the metabolitic probiotic Biosib METAPRO on protein metabolism indicators in broiler chickens

The paper presents data on the study of the influence of the metabolic probiotic (metaprobiotic) Biosib METAPRO, developed based on a complex of cultures Bifidobacterium longum and Lactobacillus plantarum at LLC “Sibbiopharm”, on the indicators of protein metabolism in broiler chickens. The study was conducted on Ross 308 cross chickens from 6 days to 35 days of age, using four groups: control and three experimental groups, to which Biosib METAPRO was additionally administered in different doses. The quantitative assessment of protein metabolism indicators in the blood serum of birds was performed photometrically using Vector-Best reagent kits. It was established that the levels of total protein, albumin, globulin, albumin/globulin ratio, alanine aminotransferase (ALT), aspartate aminotransferase (AST), de Ritis coefficient, and creatinine in broiler chickens were within the generally accepted physiological norms for birds of this age or showed insignificant deviations. Statistical analysis revealed a significant influence of the metaprobiotic on total protein, A/G ratio, ALT, AST, de Ritis coefficient, and creatinine. The most pronounced changes were observed in chickens receiving Biosib METAPRO at a dose of 0.05%. The greatest number of differences was found between the control and the 1st experimental (Biosib METAPRO at a dose of 0.05%) groups. When administering the preparation at this dosage to broiler chickens, the level of total protein increases by 9.97 g/l, there is a change in A/G ratio, an increase in ALT activity by 1.32 mmol/l⋅h, a decrease in AST by 3.76 mmol/l⋅h, normalization of the de Ritis coefficient, and an increase in the level of creatinine by 13.2 µmol/l (p0.05). The results of the study demonstrate the positive influence of the metabolic probiotic Biosib METAPRO on protein metabolism in broiler chickens, which may contribute to increasing the efficiency and sustainability of poultry meat production.