In The Presence of Risk Factors High Rate of Incidental Multifocal Microcarcinoma Detection in Solitary Thyroid Nodule and Multinodular Goitre Justifies Total Thyroidectomy

Aim: Thyroid nodules are commonly encountered with increasing age. Majority of them are benign. In the present study, our goal was to identify both the false negative rate (FNR) of preoperative cytology, radiology results, risk factors for malignancy, and the prevalence of thyroid carcinoma in cases to whom operation performed for solitary thyroid nodule (STN) with multinodular goitre (MNG) and the final histopathological report. Methods: A retrospective study among 141 patients who were operated for suspicion of thyroid cancer between 2019-2022. 118 were women (83.6%) and 23 were men (16.3%). The mean age was 50.2(23.1). Demographic characteristics and factors predicting malignancy were questioned for all patients preoperatively. Preoperative ultrasonography (US), fine needle aspiration cytology (FNAc) results and postoperative histopathology data were collected. Ultrasound features (ACR-TIRADS), FNAc results, histopathology records, risk factors and malignancy rates was registered. Statistical analysis was done with Fisher's precision and Mann-Whitney U tests. Results: 141 patients underwent total thyroidectomy for STN (n=28, 19.8%) and MNG (n=113, 80.1%). The correlation of FNAc with final histopathology revealed that FNR in MNG was more often than that of STN (33.3% vs 66.6%, p