Hemostatic Outcome Definitions in Pediatric Extracorporeal Membrane Oxygenation: Challenges in Cohorts From Rotterdam (2019–2023) and Melbourne (2016–2022)
This international comparison shows that standardizing hemostatic outcome definitions alone is insufficient for sensible comparison. Uniform interpretation of definitions, consistent frequency of outcome ascertainment, and stratification based on patient populations and ECMO practices are required. Our results highlight the granularity of detail needed for cross-center comparison of hemostatic outcomes in pediatric ECMO. Further work is needed as we move toward potential multicenter trials of pediatric ECMO.
Authors
- Fiona Newall (ORCID: https://orcid.org/0000-0003-2072-6450)
- Hui Ping Yaw (ORCID: https://orcid.org/0000-0002-9383-0219)
- Natasha Letunica (ORCID: https://orcid.org/0000-0003-3604-1536)
- Chantal Attard (ORCID: https://orcid.org/0000-0002-4428-1663)
- Joppe G. Drop (ORCID: https://orcid.org/0000-0001-6898-1595)
- Derek Best
- Joanne McKittrick
- C. Heleen van Ommen (ORCID: https://orcid.org/0000-0001-9036-039X)
- Graeme MacLaren (ORCID: https://orcid.org/0000-0002-1307-4274)
- Roberto Chiletti
- Stephen Horton (ORCID: https://orcid.org/0000-0001-5976-0942)
- Amy Johansen
- Suelyn Van Den Helm (ORCID: https://orcid.org/0000-0003-2119-9656)
- Rebecca Barton
- Warwick W. Butt (ORCID: https://orcid.org/0000-0003-3543-1014)
- Paul Monagle (ORCID: https://orcid.org/0000-0002-3970-8984)
- Matthijs de Hoog (ORCID: https://orcid.org/0000-0002-1259-581X)
- Vera Ignjatović (ORCID: https://orcid.org/0000-0002-5548-5813)
- Yves d’Udekem (ORCID: https://orcid.org/0000-0003-1851-7836)
- Willem P. de Boode (ORCID: https://orcid.org/0000-0003-3194-7005)
- Enno D. Wildschut (ORCID: https://orcid.org/0009-0005-5197-2656)
Institutions
- Royal Children's Hospital (AU)
- Children's National (US)
- Johns Hopkins University (US)
- Radboud University Nijmegen (NL)
- The University of Melbourne (AU)
- Radboud University Medical Center (NL)
- Johns Hopkins All Children's Hospital (US)
- Erasmus MC - Sophia Children’s Hospital (NL)
- National University Health System (SG)
- Murdoch Children's Research Institute (AU)
Publication Details
- Journal
- Pediatric Critical Care Medicine
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1097/pcc.0000000000003679
- Citations
- 1
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.18
Funders
- Stichting de Drie Lichten
- Medical Research Council
- National Health and Medical Research Council