Corneal Confocal and Specular Microscopic Characteristics in Primary Open-Angle Glaucoma: An Optical Coherence Tomography (OCT)-Based Case-Control Study

This study found that anterior stromal keratocyte density was positively correlated with RNFL thickness, suggesting a potential link between corneal cellular changes and glaucoma severity. Endothelial cell density was significantly lower in glaucoma patients, which may reflect the disease's impact or the effect of medications on corneal health. While corneal nerve parameters did not show significant differences, these findings highlight the importance of corneal biomechanical properties in glaucoma pathophysiology. Further studies with larger sample sizes and longer follow-up periods are needed to confirm these findings and explore the role of corneal parameters in glaucoma progression.