Succinate Regulates Exercise‐Induced Muscle Remodelling by Boosting Satellite Cell Differentiation Through Succinate Receptor 1
Our findings reveal a novel function of succinate in enhancing SC myogenic capacity via SUCNR1, leading to enhanced muscle adaptation in response to exercise. These findings provide new insights for developing pharmacological strategies to overcome muscle atrophy-related diseases.
Authors
- Da Zhou (ORCID: https://orcid.org/0000-0003-3062-5952)
- Xuejin Gao (ORCID: https://orcid.org/0000-0003-1474-4214)
- Haoyang Wang (ORCID: https://orcid.org/0000-0001-6541-7139)
- Xinying Wang (ORCID: https://orcid.org/0000-0001-5672-4700)
- Gulisudumu Maitiabula (ORCID: https://orcid.org/0000-0001-6315-091X)
- Li Zhang (ORCID: https://orcid.org/0000-0002-0090-5120)
- Yifan Shi
- Longchang Huang (ORCID: https://orcid.org/0000-0001-9136-8625)
Institutions
- Nanjing General Hospital of Nanjing Military Command (CN)
- Wuxi Fourth People's Hospital (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1002/jcsm.13670
- Citations
- 10
- Primary Topic
- Muscle Physiology and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.34
Funders
- National Natural Science Foundation of China