Development of measurement procedures for volume and flow related quantities in microfluidic devices

The precise control of fluids within channels is the common feature of the microfluidic systems, which endows them with innovative applications and makes them widely applied in multidisciplinary areas. This work carried out under the EMPIR project 20NRM02 MFMET has the focus on the development of procedures regarding volume and flow related quantity measurements using liquids such as water, simulated body fluid (SBF), and phosphate buffer saline (PBS), used for microfluidic and medical applications. The results and uncertainties obtained in the tested microfluidic devices made of glass, Cyclic Olefin Copolymer (TOPAS®) and Polydimethylsiloxane (PDMS) demonstrate the importance of traceable and comparable measurements to the characterization of microfluidic systems and their subsequent validation.