Patient-derived organoids from pancreatic cancer after pancreatectomy: Feasibility and organoid take rate in treatment-naïve periampullary tumors
In the current study, we found that PDOs could be established from resected pancreatic tumors in over half of resected periampullary tumors, and highest in PDACs. As such, generating a pancreatic cancer PDO biobank for translational research was feasible after cryopreservation.
Authors
- Kjetil Søreide (ORCID: https://orcid.org/0000-0001-7594-4354)
- Marina Alexeeva
- Marcus Roalsø (ORCID: https://orcid.org/0000-0002-4689-4412)
- Hanne R. Hagland (ORCID: https://orcid.org/0000-0002-7470-1358)
- Dordi Lea (ORCID: https://orcid.org/0000-0001-7098-3098)
- Claudia Zaharia (ORCID: https://orcid.org/0000-0002-4893-1029)
- Martin Watson (ORCID: https://orcid.org/0000-0001-9681-7805)
- Celine Oanæs
Institutions
- Stavanger University Hospital (NO)
Publication Details
- Journal
- Pancreatology
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1016/j.pan.2024.12.018
- Citations
- 7
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.98