Integrating single-cell RNA-seq and bulk RNA-seq to construct a neutrophil prognostic model for predicting prognosis and immune response in oral squamous cell carcinoma
This study elucidates the critical role of neutrophils and their associated gene modules in OSCC progression. The prognostic model provides a novel reference for patient stratification and targeted therapy. These findings offer potential new targets for OSCC diagnosis, prognosis, and immunotherapy.
Authors
- Kaicheng Yang (ORCID: https://orcid.org/0000-0003-0919-3200)
- Shixiong Peng (ORCID: https://orcid.org/0000-0002-0867-0872)
- Zifeng Cui
- Qiwen Song
- Yanping Chen (ORCID: https://orcid.org/0000-0002-5247-4967)
- Jinhang Wang
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
- Fourth Hospital of Hebei Medical University (CN)
- First Hospital of Shijiazhuang (CN)
Publication Details
- Journal
- Human Genomics
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1186/s40246-024-00712-7
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- Health Commission of Hebei Province