Exclusion of older persons from randomized controlled trials in type 2 diabetes: A cross‐sectional study
Most RCTs in type 2 diabetes have the eligibility criteria limiting the enrollment of older patients. The age limits should be eliminated and patients should be excluded based on scientifically justified criteria especially those concerning comorbidities and frailty. Moreover, the benefits and harms of new drugs in older patients with multimorbidity and/or frailty should be assessed in dedicated phase 4 trials.
Authors
- Edward Franek (ORCID: https://orcid.org/0000-0002-5953-7908)
- Danuta Kłosowska
- Jan Borysowski (ORCID: https://orcid.org/0000-0001-5256-1959)
- Leszek Pączek (ORCID: https://orcid.org/0000-0003-0160-3009)
- Michał Ordak (ORCID: https://orcid.org/0000-0001-5652-4397)
Institutions
- Medical University of Warsaw (PL)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1111/dom.16137
- Citations
- 4
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.43