Evaluation of The Prevention of Mother-to-Child Transmission (PTMC) of HIV at TheMame Abdou Sy Dabakh Hospital in Tivaouane (Senegal)

Introduction: HIV can be transmitted from mother to child in Antepartum, Intrapartum and Postpartum. Without intervention, mother-to-child transmission (MTCT) affects 15 to 30% of pregnancies worldwide. In 2012, Senegal implemented the Prevention of Mother-to-Child Transmission (PMTCT) of HIV decentralized at the regional level. It is in this context that we conducted a study to evaluate PMTCT at the Mame Abdou Sy Dabakh hospital in Tivaouane. Methodology:Retrospective descriptive study from December 2014 to December 2023 which focused on HIV PMTCT at Mame Abdou SY Dabakh hospital in Tivaouane. All pregnant women infected with HIV and children from their pregnancies were included. Failure was defined as a positive PCR at 6 weeks or a positive serology at 14 months in the child. Data collection was done from the PMTCT register and patient records, analysis via Epi Info version 7 software. Ethical considerations were respected. Result: We collected 29 pregnant women with a total of 40 procedures for 41 parous women including one twin pregnancy. The average age was 31.4 years [22 – 41]. The diagnosis of HIV infection was made in thirteen (13) patients during a pregnancy assessment (48.27%). Twenty-three (23) patients were on ARV before pregnancy (three virologic failures). Five (5) were put on treatment during pregnancy and one during delivery. Prophylaxis was carried out in 39 children (97.5%). One child did not benefit from prophylaxis. Prophylaxis was administered directly after delivery in 85% of children. Twelve children benefited from PCR which returned negative. HIV serology was carried out in twenty-seven children including one positive followed in the department. Three child deaths were reported. Conclusion: The decentralization of PMTCT has enabled the reduction of MTCT in Senegal. Efforts must be made to make available examinations and results of virologic data.