Lost penis syndrome treated with duloxetine

Sexual dysfunction is a common condition in patients with major depression. It can negatively affect quality of life, self-confidence, and relationships with partners, especially in men. Common types of sexual dysfunction include lack of sexual desire, sexual arousal disorder, erectile dysfunction, and premature ejaculation. However, some psychopathologies are rarely reported in the literature but can cause sexual dysfunction, such as the lost penis syndrome. This study aims to contribute to the literature on these rare conditions by discussing the clinical course, diagnosis, and details of duloxetine treatment of a male patient who presented to the psychiatry outpatient clinic with the complaint of loss of sensation in the penis.