Detection of a novel DNA methylation marker panel for esophageal cancer diagnosis using circulating tumor DNA
The study's findings suggested that the DNA methylation biomarkers panel holds promise as a non-invasive and convenient diagnostic test for ECa. The panel's ability to distinguish malignant tumors from benign esophageal diseases, coupled with its high sensitivity and specificity, presented opportunities to enhance the over-all diagnosis of high-risk population when in conjunction with existing detection methods.
Authors
- Kehu Yang (ORCID: https://orcid.org/0000-0001-7864-3012)
- Dongxu Chen (ORCID: https://orcid.org/0000-0002-4357-2653)
- Jie Ma (ORCID: https://orcid.org/0000-0001-5346-8457)
- Bing-wei
- Wenqun Xing (ORCID: https://orcid.org/0000-0001-6597-8649)
- Xianben Liu
- Dongfeng Yuan
- Weizhen Wang
- Guanghui Liang
- Yan Zheng (ORCID: https://orcid.org/0000-0002-1380-3211)
Institutions
- Zhengzhou University (CN)
- Henan University of Engineering (CN)
- Henan Cancer Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1186/s12885-024-13301-7
- Citations
- 1
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.57