Predicting type 2 diabetes and testosterone effects in high-risk Australian men: development and external validation of a 2-year risk model
Baseline HbA1c and 2-h OGTT glucose predict incident type 2 diabetes at 2 years in high-risk men, with risk modified independently by testosterone treatment. Men with HbA1c ≥ 5.6% (38 mmol/mol) benefit most from testosterone treatment, beyond a lifestyle program.
Authors
- Bronwyn Stuckey (ORCID: https://orcid.org/0000-0002-9109-9864)
- Ian C. Marschner (ORCID: https://orcid.org/0000-0002-6225-1572)
- David Jesudason (ORCID: https://orcid.org/0000-0002-2026-3671)
- ANTHONY C. KEECH (ORCID: https://orcid.org/0000-0002-9426-9136)
- Val Gebski (ORCID: https://orcid.org/0000-0001-8748-1844)
- Mathis Grossmann (ORCID: https://orcid.org/0000-0001-8261-3457)
- Celine Foote (ORCID: https://orcid.org/0000-0003-0203-3861)
- Kristy Pamela Robledo (ORCID: https://orcid.org/0000-0003-0213-7652)
- Bu B. Yeap (ORCID: https://orcid.org/0000-0002-7612-5892)
- David J. Handelsman (ORCID: https://orcid.org/0000-0002-4200-7476)
- Warrick J. Inder (ORCID: https://orcid.org/0000-0001-5078-4980)
- Gary Wittert (ORCID: https://orcid.org/0000-0001-6818-6065)
- Alan G. Jardine (ORCID: https://orcid.org/0000-0001-5815-9370)
- Alicia J. Jenkins (ORCID: https://orcid.org/0000-0003-0583-3717)
- Carolyn A Allan (ORCID: https://orcid.org/0000-0001-5086-0437)
- Karen Bracken (ORCID: https://orcid.org/0000-0002-6085-445X)
Institutions
- The University of Sydney (AU)
- Concord Hospital (US)
- Baker Heart and Diabetes Institute (AU)
- The University of Queensland (AU)
- The University of Melbourne (AU)
- The University of Western Australia (AU)
- Concord Repatriation General Hospital (AU)
- Austin Hospital (AU)
- Fiona Stanley Hospital (AU)
- Princess Alexandra Hospital (AU)
- Sir Charles Gairdner Hospital (AU)
- Stanley Foundation (US)
- Hudson Institute of Medical Research (AU)
- UNSW Sydney (AU)
- Cooperative Trials Group for Neuro-Oncology (AU)
- Queen Elizabeth Hospital (AU)
- The George Institute for Global Health (AU)
- South Australian Health and Medical Research Institute (AU)
- Keogh Institute for Medical Research (AU)
- Princess Alexandra Hospital (GB)
- Anzac Research Institute (AU)
- National Health and Medical Research Council (AU)
- Monash University (AU)
- The University of Adelaide (AU)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2024-12-25
- DOI
- https://doi.org/10.1093/ejendo/lvae166
- Citations
- 3
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 1.07
Funders
- Eli Lilly and Company
- WW International
- NSW Ministry of Health
- Fiona Stanley Hospital
- Eli Lilly Australia
- Medical Research Council
- National Health and Medical Research Council
- Cancer Council NSW