A distinct subgroup of AML resembling the APL immunophenotype is associated with DIC
The findings highlight the patients exhibiting the CD34<sup>-</sup>HLA-DR<sup>-</sup> immunophenotype as a unique AML subgroup with specific clinical and molecular traits, notably a predisposition to DIC, which affecting prognosis. This finding has implications for risk stratification and potential targeted therapies for AML management.
Authors
- Fuling Zhou (ORCID: https://orcid.org/0000-0003-0982-0382)
- Li Liu (ORCID: https://orcid.org/0000-0002-2762-2892)
- Pan Li (ORCID: https://orcid.org/0000-0001-6658-9207)
Institutions
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1186/s12885-024-13348-6
- Citations
- 2
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- Wuhan University
- Zhongnan Hospital of Wuhan University