Absence of Functional Autoantibodies Targeting Angiotensin <scp>II</scp> Receptor Type 1 and Endothelin‐1 Type A Receptor in Circulation and Purified <scp>IgG</scp> From Patients With Systemic Sclerosis
Overall, our study did not provide evidence to support the presence of AT<sub>1</sub>- or ET<sub>A</sub>R-activating autoantibodies in purified SSc IgG or AT<sub>1</sub>-binding autoantibodies in the circulation of patients with SSc.
Authors
- Laura H. Heitman (ORCID: https://orcid.org/0000-0002-1381-8464)
- Jeska K de Vries‐Bouwstra (ORCID: https://orcid.org/0000-0002-5624-1415)
- Eva M. Hoekstra (ORCID: https://orcid.org/0000-0002-2437-6016)
- René E. M. Toes (ORCID: https://orcid.org/0000-0002-9618-6414)
- Thomas P. Sakmar (ORCID: https://orcid.org/0000-0002-2836-8953)
- Wieke M. van Oostveen (ORCID: https://orcid.org/0000-0002-5619-4508)
- Ilana B. Kotliar (ORCID: https://orcid.org/0000-0001-9533-4828)
- Cynthia M. Fehres (ORCID: https://orcid.org/0000-0001-9020-1591)
- E. W. Nivine Levarht
Institutions
- Leiden University (NL)
- Leiden University Medical Center (NL)
- Tri-Institutional PhD Program in Chemical Biology (US)
- Oncode Institute (NL)
- Rockefeller University (US)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2024-12-25
- DOI
- https://doi.org/10.1002/art.43099
- Citations
- 8
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.40