Evaluation of the Glymphatic System in Rabbits Using Gadobutrol‐Enhanced MR Cisternography With T1 and T2 Mapping
Our findings, which indicate an absence of clearly visible arachnoid granulations in rabbits, support the significance of olfactory outflow and the glymphatic system as highlighted in recent literature. Glymphatic transport can be more effectively demonstrated using T1 mapping in rabbits. The anatomical and physiological differences between human and rodent central nervous systems must be considered when translating experimental results from rabbits to humans.
Authors
- Kadir Çetinkaya (ORCID: https://orcid.org/0000-0003-2486-4631)
- Oktay Algın (ORCID: https://orcid.org/0000-0002-3877-8366)
- Çağdaş Oto (ORCID: https://orcid.org/0000-0002-2727-3768)
- Gıyas Ayberk (ORCID: https://orcid.org/0000-0002-9258-4001)
Institutions
- Ankara University (TR)
- Bilkent University (TR)
- Tokatsu Hospital (JP)
- Ankara Yıldırım Beyazıt University (TR)
Publication Details
- Journal
- NMR in Biomedicine
- Published
- 2024-12-25
- DOI
- https://doi.org/10.1002/nbm.5314
- Citations
- 3
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.80