Evaluation of Systemic and Hematological Inflammatory Markers in Patients with Vitamin D Deficiency

Objective: This study aims to comprehensively examine the effects of vitamin D (VD) on systemic and hematological inflammatory markers. Material and Method: A total of 2889 patients with albumin, C-reactive protein (CRP), creatinine and leukocyte values within the reference ranges were included in this retrospective study. Patients were divided into three groups based on their 25-hydroxy VD levels: group-1 (VD deficiency, VD20 ng/mL (50 nmol/L)) groups. CRP-albumin ratio (CAR), neutrophil–lymphocyte ratio (NLR), platelet–lymphocyte ratio (PLR), lymphocyte-monocyte ratio (LMR), and prognostic nutritional index (PNI) were calculated. Results: The age of the groups did not differ significantly (p=0.094), while the percentage of females was significantly higher in group-1 than in group-2 and group-3 (p