ITGB3 is reduced in pregnancies with preeclampsia and its influence on biological behavior of trophoblast cells
This study suggested that ITGB3 plays an important role in promoting the proliferative, migratory, invasive, and adhesive capabilities of trophoblast cells. These findings may facilitate a more in-depth understanding of the molecular mechanisms that promote PE progression.
Authors
- Yanan Meng (ORCID: https://orcid.org/0000-0003-4569-3691)
- Xiangdi Zhang
- Chunjian Shan (ORCID: https://orcid.org/0000-0002-4355-5554)
- Beibei Zhou (ORCID: https://orcid.org/0000-0003-3873-4651)
- Yu Huang (ORCID: https://orcid.org/0000-0001-7589-0974)
- Meng Li (ORCID: https://orcid.org/0000-0003-2123-2444)
- Chunyan Li
- Qing Xia (ORCID: https://orcid.org/0000-0002-5509-6981)
- Yanrong Zhang (ORCID: https://orcid.org/0000-0002-8088-8286)
- Qiuhong Wang (ORCID: https://orcid.org/0000-0002-4852-8723)
- Mingming Lv
- Long Wei (ORCID: https://orcid.org/0000-0002-8312-277X)
- Jiaai Xia
Institutions
- Nantong University (CN)
- Nantong Maternity and Child Health Hospital (CN)
- Nanjing Maternity and Child Health Care Hospital (CN)
- Qingdao National Laboratory for Marine Science and Technology (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-12-25
- DOI
- https://doi.org/10.1186/s10020-024-01050-z
- Citations
- 3
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 1.75
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Natural Science Foundation of Jiangsu Province
- Nanjing Medical University
- Six Talent Peaks Project in Jiangsu Province
- International Union for Vacuum Science, Technique, and Applications
- Jiangsu Provincial Medical Youth Talent
- Nanjing Medical Science and Technique Development Foundation
- Young Medical Key Talents Foundation of Jiangsu Province