Exosomes secreted from amniotic mesenchymal stem cells modify trophoblast activities by delivering miR-18a-5p and regulating HRK-p53 interaction
miR-18a-5p present in AMSC-Exos could be absorbed by trophoblasts, in turn, improved their proliferation and migration, and inhibited their apoptosis by HRK downregulation.
Authors
- Huansheng Zhou
- Yuanhua Ye (ORCID: https://orcid.org/0000-0002-0517-0557)
- Yijing Chu (ORCID: https://orcid.org/0000-0002-4420-7084)
- Wenting Li (ORCID: https://orcid.org/0000-0001-5288-8310)
- Guoqiang Gao
- Jianxin Zuo (ORCID: https://orcid.org/0000-0002-3031-1075)
- Wendi Zhao
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Stem Cells
- Published
- 2024-12-25
- DOI
- https://doi.org/10.1093/stmcls/sxae087
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00