Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model
AI-enabled drug discovery revealed that HG9-91-01 could serve as a potential treatment for acute glaucoma.
Authors
- Xing Tu (ORCID: https://orcid.org/0000-0003-4354-6698)
- Yuanxu Gao (ORCID: https://orcid.org/0000-0001-5314-0195)
- Gen Li (ORCID: https://orcid.org/0000-0001-6857-0235)
- Jiahui Li (ORCID: https://orcid.org/0000-0002-7454-3257)
- Zhengchao Luo (ORCID: https://orcid.org/0009-0005-4917-2967)
- Kang Zhang
- Zixing Zou
- Simiao Zeng
Institutions
- Macau University of Science and Technology (MO)
- Sun Yat-sen University (CN)
- Chinese Academy of Sciences (CN)
- Peking University (CN)
- University of Macau (MO)
- Guangzhou Institutes of Biomedicine and Health (CN)
- University of Chinese Academy of Sciences (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Chinese Medical Journal
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1097/cm9.0000000000003387
- Citations
- 7
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.77