An Augmented Reality Visor for Intraoperative Visualization, Guidance, and Temperature Monitoring Using Fluorescence
Fluorescence-guided surgeries, including tumor resection and tissue soldering, are advancing the frontiers of surgical precision by offering enhanced control that minimizes tissue damage, improving recovery and outcomes. However, integrating fluorescence visualization with real-time temperature monitoring remains a challenge, limiting broader clinical use. We address this issue with an augmented reality (AR) visor that combines nanomaterial excitation, fluorescence detection, and temperature monitoring. Using advanced fluorescent nanoparticles like indocyanine green-doped particles and carbon nanotubes, the visor provides a comprehensive view of both the surgical field and sub-surface conditions invisible to the naked eye. This integration improves the safety and efficacy of fluorescence-guided surgeries, including laser tissue soldering, by ensuring optimal temperatures and laser guidance in real time. The presented technology enhances existing surgical techniques and supports the development of new strategies and sensing technologies in areas where traditional methods fall short, marking significant progress in precision surgery and potentially improving patient care.
Authors
- Inge Katrin Herrmann (ORCID: https://orcid.org/0000-0002-3018-6796)
- Matthias Fauconneau (ORCID: https://orcid.org/0000-0001-6318-2727)
- Robert Nißler
- Paige J. LeValley (ORCID: https://orcid.org/0000-0002-5716-6031)
- Oscar Cipolato (ORCID: https://orcid.org/0000-0003-2268-0927)
- Benjamin Suter
Institutions
- University of Zurich (CH)
- ETH Zurich (CH)
- Universitätsklinik Balgrist (CH)
- Swiss Federal Laboratories for Materials Science and Technology (CH)
Publication Details
- Journal
- Journal of Biophotonics
- Published
- 2024-12-23
- DOI
- https://doi.org/10.1002/jbio.202400417
- Citations
- 3
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.55
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Austrian Science Fund