KLF10 Induced by Hypothermic Machine Perfusion Alleviates Renal Inflammation Through BIRC2/Noncanonical NF-κB Pathway
SS can mediate KLF10 expression, whereas HMP can protect against warm ischemic injury by reducing inflammation via KLF10/BIRC2/noncanonical NF-κB pathway. Therefore, KLF10 might be a novel target for improving DCD kidney quality.
Authors
- Jianan Lan
- Qianchao Hu (ORCID: https://orcid.org/0000-0001-5694-7461)
- Qifa Ye (ORCID: https://orcid.org/0000-0002-2797-4804)
- Hao Chen (ORCID: https://orcid.org/0000-0003-3074-2235)
- Zibiao Zhong (ORCID: https://orcid.org/0009-0001-6600-1095)
- Yan Xiong (ORCID: https://orcid.org/0000-0003-0676-8267)
- Yiwen Chen (ORCID: https://orcid.org/0000-0003-4201-3072)
- Wei Zhou (ORCID: https://orcid.org/0000-0002-0879-5763)
- Zhongzhong Liu (ORCID: https://orcid.org/0000-0002-1415-7784)
Institutions
- Central South University (CN)
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
Publication Details
- Journal
- Transplantation
- Published
- 2024-12-24
- DOI
- https://doi.org/10.1097/tp.0000000000005314
- Citations
- 2
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Natural Science Foundation of China