How do immune cells shape type 1 diabetes? Insights from Mendelian randomization
The MR analysis demonstrated that seven immune cell phenotypes were associated with an increased genetic susceptibility to T1D. These findings provide a new direction for the pathogenesis of and the drug development for T1D.
Authors
- Juan Deng (ORCID: https://orcid.org/0009-0007-5963-0583)
- Xinyu Yang (ORCID: https://orcid.org/0000-0001-5117-4914)
- Yunfeng Yu (ORCID: https://orcid.org/0000-0002-0992-4694)
- Jingyi Wu (ORCID: https://orcid.org/0000-0003-2542-8567)
- Rong Yu (ORCID: https://orcid.org/0000-0001-6861-8737)
- Siyang Bai
Institutions
- Zhejiang Chinese Medical University (CN)
- Hunan University of Traditional Chinese Medicine (CN)
- First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-12-24
- DOI
- https://doi.org/10.3389/fendo.2024.1402956
- Citations
- 5
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.75
Funders
- National Natural Science Foundation of China