Metagenomic next-generation sequencing of cerebrospinal fluid: a diagnostic approach for varicella zoster virus-related encephalitis

Performing mNGS on CSF offers a rapidly and precisely diagnostic method for identifying causative pathogens in patients with VZV central nervous system (CNS) infections, especially when traditional CNS examination results are negative. Furthermore, the cases reported highlight the positive therapeutic effect of ganciclovir in treating VZV infections.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2024-12-24
DOI
https://doi.org/10.3389/fcimb.2024.1509630
Citations
2
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.77
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article

Metagenomic next-generation sequencing of cerebrospinal fluid: a diagnostic approach for varicella zoster virus-related encephalitis

Haoming Xu, Jingzhe Han, Jin Tang, K Wang
2 citations
Frontiers in Cellular and Infection Microbiology
Herpesvirus Infections and Treatments
0.77
article

Metagenomic next-generation sequencing of cerebrospinal fluid: a diagnostic approach for varicella zoster virus-related encephalitis

Haoming Xu, Jingzhe Han, Jin Tang, K Wang
article en
2 citations

Abstract

Performing mNGS on CSF offers a rapidly and precisely diagnostic method for identifying causative pathogens in patients with VZV central nervous system (CNS) infections, especially when traditional CNS examination results are negative. Furthermore, the cases reported highlight the positive therapeutic effect of ganciclovir in treating VZV infections.

Frontiers in Cellular and Infection MicrobiologyVol. 14
Hebei General Hospital (CN), Second Affiliated Hospital of Xi'an Jiaotong University (CN), Harrison International Peace Hospital (CN)
Good health and well-being
Openalex Percentile: Top 23%
Herpesvirus Infections and Treatments
0.77
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