Urinary TYROBP and HCK as genetic biomarkers for non-invasive diagnosis and therapeutic targeting in IgA nephropathy
<i>TYROBP</i> and <i>HCK</i> are promising non-invasive urinary biomarkers for IgAN. Their predictive accuracy, validated through machine learning, along with IHC confirmation and molecular docking insights, supports their potential for both diagnostic and therapeutic applications in IgAN.
Authors
- Jing Huang (ORCID: https://orcid.org/0000-0003-1378-6906)
- Bao‐Shan Hu (ORCID: https://orcid.org/0009-0007-0350-6639)
- Yangen Huang (ORCID: https://orcid.org/0000-0002-2608-7728)
- Shuting Pang (ORCID: https://orcid.org/0009-0001-2481-4581)
- Xiaolai Li
- Lianguo Ruan (ORCID: https://orcid.org/0000-0002-7122-1033)
- Junhao Mi
- Boyu Zhao (ORCID: https://orcid.org/0000-0002-2521-2443)
- Qi Tan (ORCID: https://orcid.org/0000-0002-3384-3544)
- Wei Li (ORCID: https://orcid.org/0000-0002-9991-7892)
- Shanshan Li (ORCID: https://orcid.org/0000-0001-8811-5037)
- Hong Chen (ORCID: https://orcid.org/0000-0002-2194-9042)
- Yuli Xie
- Xuesong Chen (ORCID: https://orcid.org/0009-0009-6011-6738)
- Hao Yuan (ORCID: https://orcid.org/0000-0002-1908-2988)
- Boji Xie
- Rirong Yang (ORCID: https://orcid.org/0009-0005-5349-343X)
- Mujia Jili
Institutions
- Guangxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2024-12-24
- DOI
- https://doi.org/10.3389/fgene.2024.1516513
- Citations
- 1
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.34
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangxi Province